Overview

  • Product name

  • Description

    Rabbit polyclonal to TR1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-P, ICC/IFmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to Human TR1 aa 129-223 (N terminal).
    Database link: Q7RTX1

  • Positive control

    • A549, HeLa, Jurkat and NT2D1 cell lysates; HeLa cells; Human CL1-0 xenograft tissue.
  • General notes

     This product was previously labelled as GPCR TAS1R1

     

Properties

Applications

Our Abpromise guarantee covers the use of ab155143 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 93 kDa.
IHC-P 1/100 - 1/1000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
ICC/IF 1/100 - 1/1000.

Target

  • Function

    Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate). Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses.
  • Sequence similarities

    Belongs to the G-protein coupled receptor 3 family. TAS1R subfamily.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • G protein coupled receptor 70 antibody
    • G protein-coupled receptor 70 antibody
    • G-protein coupled receptor 70 antibody
    • gm 148 antibody
    • gm148 antibody
    • GPR 70 antibody
    • GPR70 antibody
    • Krueppel related zinc finger protein 3 (HKR3 protein) antibody
    • seven transmembrane helix receptor antibody
    • Sweet taste receptor T1r antibody
    • T1R1 antibody
    • TAS1 R1 antibody
    • TAS1R1 antibody
    • Taste receptor type 1 member 1 antibody
    • taste receptor, type 1, member 1 antibody
    • TR 1 antibody
    • TR1 antibody
    • TS1R1_HUMAN antibody
    see all

Images

  • Anti-TR1 antibody (ab155143) at 1/1000 dilution + NT2D1 whole cell lysate at 30 µg

    Predicted band size: 93 kDa



    7.5% SDS PAGE
  • Immunohistochemical analysis of paraffin embedded Human CL1-0 xenograft tissue, labeling TR1 using ab155143 at a 1/100 dilution.

  • Immunofluorescence analysis of methanol fixed HeLa cells, labeling TR1 using ab155143 at a 1/200 dilution. Lower image costained with Hoerchst 33342.

References

This product has been referenced in:

  • Zhou Y  et al. Methionine Regulates mTORC1 via the T1R1/T1R3-PLCß-Ca(2+)-ERK1/2 Signal Transduction Process in C2C12 Cells. Int J Mol Sci 17:N/A (2016). WB ; Mouse . Read more (PubMed: 27727170) »
See 1 Publication for this product

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