Key features and details
- Rabbit polyclonal to TR1
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-TR1 antibody
See all TR1 primary antibodies
DescriptionRabbit polyclonal to TR1
SpecificityBLAST analysis of the peptide immunogen showed no homology with other human proteins, except TAS1R2 (69%).
Tested applicationsSuitable for: IHC-Pmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat, Rabbit, Horse, Hamster, Dog, Pig, Monkey
Synthetic peptide corresponding to Human TR1. 16 amino acid peptide from 3rd cytoplasmic domain of human TAS1R1.
Database link: Q7RTX1
- IHC-P: Human colon carcinoma, non-small cell lung carcinoma and testis tissue.
This product was previously labelled as GPCR TAS1R1
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.099% Sodium azide
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab230788 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||Use a concentration of 6 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.|
FunctionPutative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate). Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses.
Sequence similaritiesBelongs to the G-protein coupled receptor 3 family. TAS1R subfamily.
Cellular localizationCell membrane.
- Information by UniProt
- G protein coupled receptor 70 antibody
- G protein-coupled receptor 70 antibody
- G-protein coupled receptor 70 antibody
Formalin-fixed paraffin-embedded human colon carcinoma tissue stained for TR1 with ab230788 at 6 μg/ml in immunohistochemical analysis.
Formalin-fixed paraffin-embedded human non-small cell lung carcinoma tissue stained for TR1 with ab230788 at 6 μg/ml in immunohistochemical analysis.
Formalin-fixed paraffin-embedded human testis tissue stained for TR1 with ab230788 at 6 μg/ml in immunohistochemical analysis.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab230788 has been referenced in 2 publications.
- Tian M et al. Branched chain amino acids stimulate gut satiety hormone cholecystokinin secretion through activation of the umami taste receptor T1R1/T1R3 using an in vitro porcine jejunum model. Food Funct 10:3356-3367 (2019). PubMed: 31098606
- Tian M et al. Dietary Branched-Chain Amino Acids Regulate Food Intake Partly through Intestinal and Hypothalamic Amino Acid Receptors in Piglets. J Agric Food Chem 67:6809-6818 (2019). PubMed: 31134808