Overview

  • Product name

  • Description

    Human polyclonal to TRAF3IP1
  • Host species

    Human
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to Human TRAF3IP1 aa 332-406.
    Sequence:

    ISTRASKSLTTKTSKRRSKNSVEGRKEDNISAKSLDSIVSGINNEPNQET TTSEIGTKEANINSTSISDDNSASL


    Database link: Q8TDR0

  • Positive control

    • IHC-P: Human fallopian tube tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab224542 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/20 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    Play an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding. Recruits TRAF3 and DISC1 to the microtubules.
  • Tissue specificity

    Ubiquitous.
  • Sequence similarities

    Belongs to the TRAF3IP1 family.
  • Cellular localization

    Cytoplasm > cytoskeleton. Microtubules.
  • Information by UniProt
  • Database links

  • Alternative names

    • Interleukin 13 receptor alpha 1 binding protein 1 antibody
    • Interleukin-13 receptor alpha 1-binding protein 1 antibody
    • Microtubule interacting protein that associates with TRAF3 antibody
    • Microtubule-interacting protein associated with TRAF3 antibody
    • MIP T3 antibody
    • MIP-T3 antibody
    • MIPT3 antibody
    • MIPT3_HUMAN antibody
    • TNF receptor associated factor 3 interacting protein 1 antibody
    • TRAF3-interacting protein 1 antibody
    • Traf3ip1 antibody
    see all

Images

  • Paraffin-embedded human fallopian tuce tissue stained for TRAF3IP1 with ab224542 at 1/20 dilution in immunohistochemical analysis.

References

ab224542 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab224542.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up