Anti-TRAF3IP1 antibody - N-terminal (ab153860)
Key features and details
- Rabbit polyclonal to TRAF3IP1 - N-terminal
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-TRAF3IP1 antibody - N-terminal -
Description
Rabbit polyclonal to TRAF3IP1 - N-terminal -
Host species
Rabbit -
Tested applications
Suitable for: WB, IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Cow -
Immunogen
Recombinant fragment, corresponding to a region within N terminal amino acids 1-223 of Human TRAF3IP1.
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Positive control
- U87-MG whole cell lysate; H441 xenograft.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab153860 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/3000. Predicted molecular weight: 79 kDa.
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IHC-P |
1/100 - 1/1000. Perform heat mediated antigen retrieval before commencing with IHC staining protocol using 10mM Citrate buffer (pH6.0) or Tris-EDTA buffer (pH8.0).
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Notes |
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WB
1/500 - 1/3000. Predicted molecular weight: 79 kDa. |
IHC-P
1/100 - 1/1000. Perform heat mediated antigen retrieval before commencing with IHC staining protocol using 10mM Citrate buffer (pH6.0) or Tris-EDTA buffer (pH8.0). |
Target
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Function
Play an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding. Recruits TRAF3 and DISC1 to the microtubules. -
Tissue specificity
Ubiquitous. -
Sequence similarities
Belongs to the TRAF3IP1 family. -
Cellular localization
Cytoplasm > cytoskeleton. Microtubules. - Information by UniProt
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Database links
- Entrez Gene: 504984 Cow
- Entrez Gene: 26146 Human
- Omim: 607380 Human
- SwissProt: Q8TDR0 Human
- Unigene: 631898 Human
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Alternative names
- Interleukin 13 receptor alpha 1 binding protein 1 antibody
- Interleukin-13 receptor alpha 1-binding protein 1 antibody
- Microtubule interacting protein that associates with TRAF3 antibody
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Images
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab153860 has not yet been referenced specifically in any publications.