Overview

  • Product name

    Anti-TRAF6BP/TAX1BP1 antibody
    See all TRAF6BP/TAX1BP1 primary antibodies
  • Description

    Rabbit polyclonal to TRAF6BP/TAX1BP1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IP, WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow, Orangutan
  • Immunogen

    Synthetic peptide within Human TRAF6BP/TAX1BP1 aa 739-789. The exact sequence is proprietary. NP_006015.4
    Database link: Q86VP1

  • Positive control

    • WB: HeLa, HEK-293T and Jurkat whole cell lysates. IP: HeLa whole cell lysate.
  • General notes

     This product was previously labelled as TRAF6BP

     

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    Preservative: 0.09% Sodium azide
    Constituent: Tris citrate/phosphate

    pH 7 to 8
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Purification notes

    ab245636 was affinity purified using an epitope specific to TRAF6BP/TAX1BP1 immobilized on solid support.
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab245636 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP Use at 2-10 µg/mg of lysate.
WB 1/2000 - 1/10000. Predicted molecular weight: 91 kDa.

Target

  • Function

    Inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degraded by caspase-3-like family proteins upon TNF-induced apoptosis. May also play a role in the pro-inflammatory cytokine IL-1 signaling cascade.
  • Tissue specificity

    Expressed in all tissues tested.
  • Information by UniProt
  • Database links

  • Alternative names

    • 1200003J11Rik antibody
    • 1700069J21Rik antibody
    • Aa1076 antibody
    • AA930106 antibody
    • CALCOCO 3 antibody
    • CALCOCO3 antibody
    • D6Ertd404e antibody
    • D6Ertd772e antibody
    • Human T cell leukemia virus type 1-binding protein antibody
    • Liver regeneration-related protein LRRG004 antibody
    • MGC94031 antibody
    • PRO0105 antibody
    • T6BP antibody
    • Tax1 (human T cell leukemia virus type I) binding protein antibody
    • Tax1 (human T cell leukemia virus type I) binding protein 1 antibody
    • Tax1 binding protein 1 antibody
    • Tax1 binding protein antibody
    • Tax1-binding protein 1 antibody
    • Tax1-binding protein 1 homolog antibody
    • TAX1BP1 antibody
    • TAX1BP1 protein antibody
    • tax1bp1b antibody
    • TAXB1_HUMAN antibody
    • TRAF 6 binding protein antibody
    • TRAF6 binding protein antibody
    • TRAF6 binding protein T6BP antibody
    • TRAF6-binding protein antibody
    • TRAF6-interacting protein antibody
    • TXBP 151 antibody
    • TXBP151 antibody
    • wu:fc20c12 antibody
    • wu:fc56e11 antibody
    • zgc:73219 antibody
    • zgc:77129 antibody
    see all

Images

  • All lanes : Anti-TRAF6BP/TAX1BP1 antibody (ab245636) at 0.1 µg/ml

    Lane 1 : HeLa (human epithelial cell line from cervix adenocarcinoma) whole cell lysate at 50 µg
    Lane 2 : HeLa whole cell lysate at 15 µg
    Lane 3 : HEK-293T (human epithelial cell line from embryonic kidney transformed with large T antigen) whole cell lysate at 50 µg
    Lane 4 : Jurkat (human T cell leukemia cell line from peripheral blood) whole cell lysate at 50 µg

    Developed using the ECL technique.

    Predicted band size: 91 kDa


    Exposure time: 30 seconds
  • TRAF6BP/TAX1BP1 was immunoprecipitated from HeLa (human epithelial cell line from cervix adenocarcinoma) whole cell lysate (1 mg for IP, 20% of IP loaded) with ab245636 at 6 µg/mg lysate. Western blot was performed from the immunoprecipitate using ab245636 at 1 µg/ml.

    Lane 1: ab245636 IP in HeLa whole cell lysate.
    Lane 2: Control IgG IP in HeLa whole cell lysate.

    Detection: Chemiluminescence with exposure time of 10 seconds.

References

This product has been referenced in:

  • Hu S  et al. Structure of Myosin VI/Tom1 complex reveals a cargo recognition mode of Myosin VI for tethering. Nat Commun 10:3459 (2019). Read more (PubMed: 31371777) »
See 1 Publication for this product

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