Recombinant
RabMAb

Recombinant Anti-TRAF6BP/TAX1BP1 antibody [EPR13287(B)] - C-terminal (ab176572)

Overview

  • Product name

    Anti-TRAF6BP/TAX1BP1 antibody [EPR13287(B)] - C-terminal
    See all TRAF6BP/TAX1BP1 primary antibodies
  • Description

    Rabbit monoclonal [EPR13287(B)] to TRAF6BP/TAX1BP1 - C-terminal
  • Host species

    Rabbit
  • Tested applications

    Suitable for: ICC/IF, WBmore details
    Unsuitable for: Flow Cyt,IHC-P or IP
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human TRAF6BP/TAX1BP1 aa 750 to the C-terminus (C terminal) (Cysteine residue). The exact sequence is proprietary. Isoform 1
    Database link: Q86VP1

  • Positive control

    • HepG2, A549, 293T and U937 cell lysates; A549 cells.
  • General notes

     

     

     This product was previously labelled as TRAF6BP

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    We are constantly working hard to ensure we provide our customers with best in class antibodies. As a result of this work we are pleased to now offer this antibody in purified format. We are in the process of updating our datasheets. The purified format is designated 'PUR' on our product labels. If you have any questions regarding this update, please contact our Scientific Support team.

    This product is a recombinant rabbit monoclonal antibody.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.20
    Preservative: 0.01% Sodium azide
    Constituents: 59% PBS, 40% Glycerol, 0.5% BSA
  • Concentration information loading...
  • Purity

    Protein A purified
  • Clonality

    Monoclonal
  • Clone number

    EPR13287(B)
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab176572 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF 1/50 - 1/100.
WB 1/1000 - 1/5000. Predicted molecular weight: 91 kDa.
  • Application notes
    Is unsuitable for Flow Cyt,IHC-P or IP.
  • Target

    • Function

      Inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degraded by caspase-3-like family proteins upon TNF-induced apoptosis. May also play a role in the pro-inflammatory cytokine IL-1 signaling cascade.
    • Tissue specificity

      Expressed in all tissues tested.
    • Information by UniProt
    • Database links

    • Alternative names

      • 1200003J11Rik antibody
      • 1700069J21Rik antibody
      • Aa1076 antibody
      • AA930106 antibody
      • CALCOCO 3 antibody
      • CALCOCO3 antibody
      • D6Ertd404e antibody
      • D6Ertd772e antibody
      • Human T cell leukemia virus type 1-binding protein antibody
      • Liver regeneration-related protein LRRG004 antibody
      • MGC94031 antibody
      • PRO0105 antibody
      • T6BP antibody
      • Tax1 (human T cell leukemia virus type I) binding protein antibody
      • Tax1 (human T cell leukemia virus type I) binding protein 1 antibody
      • Tax1 binding protein 1 antibody
      • Tax1 binding protein antibody
      • Tax1-binding protein 1 antibody
      • Tax1-binding protein 1 homolog antibody
      • TAX1BP1 antibody
      • TAX1BP1 protein antibody
      • tax1bp1b antibody
      • TAXB1_HUMAN antibody
      • TRAF 6 binding protein antibody
      • TRAF6 binding protein antibody
      • TRAF6 binding protein T6BP antibody
      • TRAF6-binding protein antibody
      • TRAF6-interacting protein antibody
      • TXBP 151 antibody
      • TXBP151 antibody
      • wu:fc20c12 antibody
      • wu:fc56e11 antibody
      • zgc:73219 antibody
      • zgc:77129 antibody
      see all

    Images

    • All lanes : Anti-TRAF6BP/TAX1BP1 antibody [EPR13287(B)] - C-terminal (ab176572) at 1/1000 dilution

      Lane 1 : HepG2 cell lysate
      Lane 2 : A549 cell lysate
      Lane 3 : 293T cell lysate
      Lane 4 : U937 cell lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      All lanes : Goat anti-rabbit HRP at 1/2000 dilution

      Developed using the ECL technique.

      Predicted band size: 91 kDa

    • Immunofluorescence analysis of A549 cells labeling TRAF6BP/TAX1BP1 using ab176572 at a 1/50 dilution (green). DAPI nuclear staining (blue).

    References

    This product has been referenced in:

    • Lim J  et al. Autophagy regulates inflammatory programmed cell death via turnover of RHIM-domain proteins. Elife 8:N/A (2019). Read more (PubMed: 31287416) »
    • Choi YB  et al. TAX1BP1 Restrains Virus-Induced Apoptosis by Facilitating Itch-Mediated Degradation of the Mitochondrial Adaptor MAVS. Mol Cell Biol 37:N/A (2017). Read more (PubMed: 27736772) »
    See all 2 Publications for this product

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab176572.
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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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