Product nameAnti-TRAFD1 antibody [EPR12322]
See all TRAFD1 primary antibodies
DescriptionRabbit monoclonal [EPR12322] to TRAFD1
Tested applicationsSuitable for: IHC-P, WBmore details
Unsuitable for: ICC/IF or IP
Species reactivityReacts with: Human
Recombinant fragment within Human TRAFD1. The exact sequence is proprietary.
Database link: O14545
- Human thymus; Human skeletal muscle; Human fetal brain; Human lymph node and Human spleen tissue lysates; Human brain tissue; Human cervix carcinoma tissue.
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.
This product is a recombinant rabbit monoclonal antibody.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol, 0.05% BSA, 50% Tissue culture supernatant
PurityTissue culture supernatant
Our Abpromise guarantee covers the use of ab174853 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/50 - 1/100.|
|WB||1/1000 - 1/10000. Predicted molecular weight: 65 kDa.|
FunctionNegative feedback regulator that controls excessive innate immune responses. Regulates both Toll-like receptor 4 (TLR4) and DDX58/RIG1-like helicases (RLH) pathways. May inhibit the LTR pathway by direct interaction with TRAF6 and attenuation of NF-kappa-B activation. May negatively regulate the RLH pathway downstream from MAVS and upstream of NF-kappa-B and IRF3.
Sequence similaritiesContains 1 TRAF-type zinc finger.
- Information by UniProt
- FLN29 antibody
- FLN29 gene product antibody
- Protein FLN29 antibody
Immunohistochemical analysis of paraffin-embedded Human cervix carcinoma tissue labeling TRAFD1 using ab174853 at 1/50 dilution.
Immunohistochemical analysis of paraffin-embedded Human brain tissue labeling TRAFD1 using ab174853 at 1/50 dilution.
All lanes : Anti-TRAFD1 antibody [EPR12322] (ab174853) at 1/1000 dilution
Lane 1 : Human fetal thymus lysate
Lane 2 : Human skeletal muscle lysate
Lane 3 : Human fetal brain lysate
Lane 4 : Human lymph node lysate
Lane 5 : Human spleen lysate
Lysates/proteins at 10 µg per lane.
Predicted band size: 65 kDa
ab174853 has not yet been referenced specifically in any publications.