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I would like to know if this antibody is an agonist vs antagonist of TRAIL receptor. You mentioned functional studies on the datasheet. Many thanks,
Asked on Oct 28 2002
This antibody was raised against soluble recombinant TRAIL /APO-2L (extracellular domain). It completely neutralizes apoptosis in cells induced by TRAIL (e.g. by soluble recombinant human TRAIL) that is why datasheet states functional application.
Answered on Oct 30 2002