Anti-Transferrin antibody (ab19177)

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Key features and details

  • Goat polyclonal to Transferrin
  • Reacts with: Human
  • Isotype: IgG

Overview

  • Product name

    Anti-Transferrin antibody
    See all Transferrin primary antibodies

  • Description

    Goat polyclonal to Transferrin

  • Host species

    Goat

  • Species reactivity

    Reacts with: Human

  • Immunogen

    Full length native protein (purified) (Human).

  • General notes

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Properties

Target

  • Function

    Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation.

  • Tissue specificity

    Expressed by the liver and secreted in plasma.

  • Involvement in disease

    Defects in TF are the cause of atransferrinemia (ATRAF) [MIM:209300]. Atransferrinemia is rare autosomal recessive disorder characterized by iron overload and hypochromic anemia.

  • Sequence similarities

    Belongs to the transferrin family.
    Contains 2 transferrin-like domains.

  • Cellular localization

    Secreted.
  • Information by UniProt

  • Database links

    • Alternative names

      • Apotransferrin antibody
      • Beta 1 metal binding globulin antibody
      • Beta-1 metal-binding globulin antibody
      • DKFZp781D0156 antibody
      • PRO1400 antibody
      • PRO1557 antibody
      • PRO2086 antibody
      • Serotransferrin antibody
      • Serotransferrin precursor antibody
      • Siderophilin antibody
      • TF antibody
      • TFQTL1 antibody
      • Transferin antibody
      • Transferrin antibody
      • TRFE_HUMAN antibody
      see all

    References (0)

    Publishing research using ab19177? Please let us know so that we can cite the reference in this datasheet.

    ab19177 has not yet been referenced specifically in any publications.

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