Key features and details
- Rabbit polyclonal to Transferrin
- Suitable for: WB, ELISA
- Reacts with: Human
- Isotype: IgG
Product nameAnti-Transferrin antibody
See all Transferrin primary antibodies
DescriptionRabbit polyclonal to Transferrin
Tested applicationsSuitable for: WB, ELISAmore details
Species reactivityReacts with: Human
Full length Human transferrin, partially iron saturated.
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferpH: 7.40
Constituent: 0.0268% PBS
Concentration information loading...
PurityProtein G purified
Our Abpromise guarantee covers the use of ab66952 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/50000. Detects a band of approximately 77 kDa (predicted molecular weight: 77 kDa).|
|ELISA||1/150000 - 1/300000. Coating antigen 800ng/well|
FunctionTransferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation.
Tissue specificityExpressed by the liver and secreted in plasma.
Involvement in diseaseDefects in TF are the cause of atransferrinemia (ATRAF) [MIM:209300]. Atransferrinemia is rare autosomal recessive disorder characterized by iron overload and hypochromic anemia.
Sequence similaritiesBelongs to the transferrin family.
Contains 2 transferrin-like domains.
- Information by UniProt
- Apotransferrin antibody
- Beta 1 metal binding globulin antibody
- Beta-1 metal-binding globulin antibody
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab66952 has been referenced in 3 publications.
- Yang H et al. Obesity is associated with copper elevation in serum and tissues. Metallomics 11:1363-1371 (2019). PubMed: 31249997
- Di Luca A et al. 2D DIGE proteomic analysis of early post mortem muscle exudate highlights the importance of the stress response for improved water-holding capacity of fresh pork meat. Proteomics 13:1528-44 (2013). PubMed: 23456991
- Pitek AS et al. Transferrin coated nanoparticles: study of the bionano interface in human plasma. PLoS One 7:e40685 (2012). PubMed: 22829881