Key features and details
- Rabbit polyclonal to Transglutaminase 5/TGM5
- Suitable for: WB, ICC/IF
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Product nameAnti-Transglutaminase 5/TGM5 antibody
See all Transglutaminase 5/TGM5 primary antibodies
DescriptionRabbit polyclonal to Transglutaminase 5/TGM5
Tested applicationsSuitable for: WB, ICC/IFmore details
Species reactivityReacts with: Mouse, Rat, Human
Recombinant full length protein corresponding to Human Transglutaminase 5/TGM5 aa 260-720 (C terminal).
Database link: O43548
This product was previously labelled as Transglutaminase 5
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 50% Glycerol
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab210772 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/2000. Predicted molecular weight: 81 kDa.|
|ICC/IF||1/50 - 1/100.|
FunctionCatalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Contributes to the formation of the cornified cell envelope of keratinocytes.
Tissue specificityExpressed in foreskin keratinocytes.
Involvement in diseaseDefects in TGM5 are a cause of peeling skin syndrome type A (APSS) [MIM:609796]. A non-inflammatory form of peeling skin syndrome, a genodermatosis characterized by the continuous shedding of the outer layers of the epidermis. In APSS patients, skin peeling is strictly limited to the dorsa of the hands and feet, and it is accompanied by accompanied by painless erythema and spontaneous non-scarring healing. Ultrastructural and histological analysis shows a level of blistering high in the epidermis at the stratum granulosum-stratum corneum junction.
Sequence similaritiesBelongs to the transglutaminase superfamily. Transglutaminase family.
Cellular localizationCytoplasm. Associated with intermediate filaments.
- Information by UniProt
- Protein glutamine gamma glutamyltransferase 5 antibody
- Protein-glutamine gamma-glutamyltransferase 5 antibody
- PSS2 antibody
All lanes : Anti-Transglutaminase 5/TGM5 antibody (ab210772) at 1/500 dilution
Lane 1 : Mouse liver extract
Lane 2 : Mouse heart extract
Lane 3 : Rat liver extract
Lane 4 : Rat heart extract
Predicted band size: 81 kDa
Immunofluorescent analysis of U2OS cells labeling Transglutaminase 5/TGM5 with ab210772 at 1/50 dilution (green). Blue: DAPI for nuclear staining.
ab210772 has not yet been referenced specifically in any publications.