Overview

  • Product name

    Anti-TRAP alpha/TRAPA antibody [EPR5604]
    See all TRAP alpha/TRAPA primary antibodies
  • Description

    Rabbit monoclonal [EPR5604] to TRAP alpha/TRAPA
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC,IHC-P or IP
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human TRAP alpha/TRAPA aa 250 to the C-terminus (C terminal). The exact sequence is proprietary.
    Database link: P43307

  • Positive control

    • HL60 and HepG2 cell lysates.
  • General notes

     

     

     This product was previously labelled as TRAP alpha

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • Dissociation constant (KD)

    KD = 3.30 x 10 -11 M
    Learn more about KD
  • Storage buffer

    pH: 7.20
    Preservative: 0.01% Sodium azide
    Constituents: 9% PBS, 40% Glycerol, 0.05% BSA, 50% Tissue culture supernatant
  • Purity

    Tissue culture supernatant
  • Clonality

    Monoclonal
  • Clone number

    EPR5604
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab126775 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Detects a band of approximately 34 kDa (predicted molecular weight: 32 kDa).
  • Application notes
    Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
  • Target

    • Function

      TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. May be involved in the recycling of the translocation apparatus after completion of the translocation process or may function as a membrane-bound chaperone facilitating folding of translocated proteins.
    • Sequence similarities

      Belongs to the TRAP-alpha family.
    • Domain

      Shows a remarkable charge distribution with the N-terminus being highly negatively charged, and the cytoplasmic C-terminus positively charged.
    • Cellular localization

      Endoplasmic reticulum membrane.
    • Information by UniProt
    • Database links

    • Alternative names

      • DKFZp781N23103 antibody
      • FLJ14232 antibody
      • FLJ22100 antibody
      • FLJ23034 antibody
      • FLJ78242 antibody
      • FLJ93042 antibody
      • PGP35 antibody
      • Signal sequence receptor alpha antibody
      • Signal sequence receptor alpha subunit antibody
      • Signal sequence receptor subunit alpha antibody
      • SSR 1 antibody
      • SSR alpha antibody
      • SSR-alpha antibody
      • SSR1 antibody
      • SSRA_HUMAN antibody
      • SSRalpha antibody
      • Translocon associated protein alpha antibody
      • Translocon associated protein alpha subunit antibody
      • Translocon associated protein subunit alpha antibody
      • Translocon-associated protein subunit alpha antibody
      • TRAP a antibody
      • TRAP-alpha antibody
      • TRAPa antibody
      • TRAPalpha antibody
      see all

    Images

    • All lanes : Anti-TRAP alpha/TRAPA antibody [EPR5604] (ab126775) at 1/1000 dilution

      Lane 1 : HL60 cell lysate
      Lane 2 : HepG2 cell lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      All lanes : Goat anti-Rabbit HRP

      Predicted band size: 32 kDa

    • Equilibrium disassociation constant (KD)
      Learn more about KD

      Click here to learn more about KD

    References

    This product has been referenced in:

    • Zhou L  et al. MicroRNA-100-5p inhibits osteoclastogenesis and bone resorption by regulating fibroblast growth factor 21. Int J Mol Med 43:727-738 (2019). Read more (PubMed: 30535435) »
    See 1 Publication for this product

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab126775.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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