Recombinant Anti-TRAPPC2 antibody [EPR3401] (ab111848)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR3401] to TRAPPC2
- Suitable for: WB
- Reacts with: Human
Related conjugates and formulations
Overview
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Product name
Anti-TRAPPC2 antibody [EPR3401]
See all TRAPPC2 primary antibodies -
Description
Rabbit monoclonal [EPR3401] to TRAPPC2 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details
Unsuitable for: Flow Cyt,ICC/IF,IHC-P or IP -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat -
Immunogen
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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Positive control
- Human spleen, Raji, and Daudi cell lysates.
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General notes
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
Storage buffer
pH: 7.20
Preservative: 0.05% Sodium azide
Constituents: 0.1% BSA, 40% Glycerol (glycerin, glycerine), 9.85% Tris glycine, 50% Tissue culture supernatant -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Monoclonal -
Clone number
EPR3401 -
Isotype
IgG -
Research areas
Associated products
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Alternative Versions
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab111848 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/1000 - 1/10000. Predicted molecular weight: 16 kDa.
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Notes |
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WB
1/1000 - 1/10000. Predicted molecular weight: 16 kDa. |
Target
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Relevance
Function: Prevents MBP1-mediated transcriptional repression and antagonizes MBP1-mediated cell death. May play a role in vesicular transport from endoplasmic reticulum to Golgi. Tissue specificity: Widely expressed. Disease: Defects in TRAPPC2 are the cause of spondyloepiphyseal dysplasia tarda (SEDT) [MIM:313400]. SEDT is an X-linked recessive disorder of endochondral bone formation. Similarity: Belongs to the TRAPP small subunits family. Sedlin subfamily. -
Cellular localization
Cytoplasm > perinuclear region. Endoplasmic reticulum. Golgi apparatus. Localized in perinuclear granular structures. -
Database links
- Entrez Gene: 6399 Human
- Entrez Gene: 66050 Mouse
- Entrez Gene: 66226 Mouse
- Entrez Gene: 501550 Rat
- Omim: 300202 Human
- SwissProt: O14582 Human
- SwissProt: P0DI81 Human
- SwissProt: P0DI82 Human
see all -
Alternative names
- hYP38334 antibody
- MBP 1 interacting protein 2A antibody
- MBP-1-interacting protein 2A antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab111848 has been referenced in 1 publication.
- Ke Y et al. Trappc9 deficiency in mice impairs learning and memory by causing imbalance of dopamine D1 and D2 neurons. Sci Adv 6:N/A (2020). PubMed: 33208359