Key features and details
- Rabbit polyclonal to Treslin - C-terminal
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-Treslin antibody - C-terminal
See all Treslin primary antibodies
DescriptionRabbit polyclonal to Treslin - C-terminal
Tested applicationsSuitable for: WB, IHC-Pmore details
Species reactivityReacts with: Human
Synthetic peptide within Human Treslin (C terminal). The exact sequence is proprietary. Peptide corresponds to 19 amino acids near the carboxy terminus (NP_689472).
Database link: Q7Z2Z1
- Human small intestine tissue and tissue lysate.
Previously labelled as C15orf42.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.02% Sodium azide
Constituent: 99% PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab191850 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 220 kDa (predicted molecular weight: 211 kDa).|
|IHC-P||Use a concentration of 5 µg/ml.|
FunctionRegulator of DNA replication and S/M and G2/M checkpoints. Regulates the triggering of DNA replication initiation via its interaction with TOPBP1 by participating to CDK2-mediated loading of CDC45L onto replication origins. Required for the transition from pre-replication complex (pre-RC) to pre-initiation complex (pre-IC). Required to prevent mitotic entry after treatment with ionizing radiation.
Sequence similaritiesBelongs to the treslin family.
Cellular localizationNucleus. Associates with chromatin.
- Information by UniProt
- C15orf42 antibody
- chromosome 15 open reading frame 42 antibody
- replication-stimulating protein antibody
Anti-Treslin antibody - C-terminal (ab191850) at 1 µg/ml + Human small intestine tissue lysate at 15 µg
Developed using the ECL technique.
Predicted band size: 211 kDa
Observed band size: 220 kDa why is the actual band size different from the predicted?
Immunohistochemistry analysis of human small intestine tissue, labeling Treslin using ab191850 at 20 μg/mL.
Immunohistochemical analysis of paraffin-embedded Human small intestine tissue, labeling Treslin using ab191850 at 5 μg/mL.
ab191850 has not yet been referenced specifically in any publications.