Overview

  • Product name

  • Description

    Goat polyclonal to TRIB1
  • Host species

    Goat
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Monkey, Opossum, Elephant
  • Immunogen

    Synthetic peptide:

    C-TSDQIVPEYQEDSD

    (with a Cysteine residue linker), corresponding to C terminal amino acids 353-366 of Human TRIB1 (NP_079471.1).

  • Positive control

    • IHC-P: Human Spleen tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab134809 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 3.75 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    Interacts with MAPK kinases and regulates activation of MAP kinases. May not display kinase activity.
  • Tissue specificity

    Expressed in most human tissues with the highest levels in skeletal muscle, thyroid gland, pancreas, peripheral blood leukocytes, and bone marrow.
  • Sequence similarities

    Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. Tribbles subfamily.
    Contains 1 protein kinase domain.
  • Domain

    The protein kinase domain is predicted to be catalytically inactive.
  • Information by UniProt
  • Database links

  • Alternative names

    • C8FW antibody
    • G-protein-coupled receptor-induced gene 2 protein antibody
    • GIG-2 antibody
    • GIG2 antibody
    • SKIP1 antibody
    • TRB-1 antibody
    • TRB1 antibody
    • Trib1 antibody
    • TRIB1_HUMAN antibody
    • Tribbles homolog 1 antibody
    see all

Images

  • Immunohistochemistry analysis of Formalin fixed and Paraffin Embedded (IHC-P) Human Spleen tissue labelling TRIB1 with ab134809 at 3.75 µg/ml.

References

This product has been referenced in:

  • Lin ZY  et al. MicroRNA-224 inhibits progression of human prostate cancer by downregulating TRIB1. Int J Cancer 135:541-50 (2014). WB . Read more (PubMed: 24382668) »
See 1 Publication for this product

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