Overview

  • Product name

  • Description

    Rabbit polyclonal to TRIB1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow, Monkey
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 104-372 of Human TRIB1.

  • Positive control

    • Molt-4 whole cell lysate; Human Cal27 xenograft.

Properties

Applications

Our Abpromise guarantee covers the use of ab137717 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 41 kDa.
IHC-P 1/100 - 1/1000. Perform heat mediated antigen retrieval using 10mM Citrate buffer (pH6.0) or Tris-EDTA buffer (pH8.0) before commencing with IHC staining protocol..

Target

  • Function

    Interacts with MAPK kinases and regulates activation of MAP kinases. May not display kinase activity.
  • Tissue specificity

    Expressed in most human tissues with the highest levels in skeletal muscle, thyroid gland, pancreas, peripheral blood leukocytes, and bone marrow.
  • Sequence similarities

    Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. Tribbles subfamily.
    Contains 1 protein kinase domain.
  • Domain

    The protein kinase domain is predicted to be catalytically inactive.
  • Information by UniProt
  • Database links

  • Alternative names

    • C8FW antibody
    • G-protein-coupled receptor-induced gene 2 protein antibody
    • GIG-2 antibody
    • GIG2 antibody
    • SKIP1 antibody
    • TRB-1 antibody
    • TRB1 antibody
    • Trib1 antibody
    • TRIB1_HUMAN antibody
    • Tribbles homolog 1 antibody
    see all

Images

  • Anti-TRIB1 antibody (ab137717) at 1/1000 dilution + Molt-4 whole cell lysate at 30 µg

    Predicted band size: 41 kDa



    10% SDS PAGE
  • Immunohistochemical analysis of paraffin-embedded Human Cal27 xenograft labelling TRIB1 with ab137717 at 1/100 dilution.

References

This product has been referenced in:

  • Fu Y  et al. Tribbles homolog 1 enhances cholesterol efflux from oxidized low-density lipoprotein-loaded THP-1 macrophages. Exp Ther Med 14:862-866 (2017). Read more (PubMed: 28673011) »
See 1 Publication for this product

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