Trichostatin A (DMSO solution), histone deacetylase inhibitor (ab146598)

Overview

  • Product name

    Trichostatin A (DMSO solution), histone deacetylase inhibitor
  • Description

    Potent, selective histone deacetylase inhibitor
  • Biological description

    Potent, selective histone deacetylase (HDAC) inhibitor (Ki = 3.4 nM). Induces cell proliferation, differentiation and apoptosis in vitro. Anticancer and antifungal agent. Active in vivo and in vitro.

    Also available as a solid (ab120850).
  • Purity

    > 99%
  • CAS Number

    58880-19-6
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (2E,4E,6R)-7-[4-(Dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide
  • Molecular weight

    302.37
  • Molecular formula

    C17H22N2O3
  • PubChem identifier

    444732
  • Storage instructions

    Store at -20°C. Store In the Dark. Store under desiccating conditions. This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes.
  • Solubility overview

    Supplied in DMSO (10 mM)
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C[C@H](/C=C(\C)/C=C/C(=O)NO)C(=O)C1=CC=C(C=C1)N(C)C
  • Source

    Synthetic

References

ab146598 has not yet been referenced specifically in any publications.

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