Key features and details
- Selective, potent inhibitor of Akt activation
- CAS Number: 35943-35-2
- Purity: > 98%
- Soluble in DMSO to 75 mM and in ethanol to 10 mM
- Form / State: Solid
- Source: Synthetic
Product nameTriciribine, inhibitor of Akt activation
DescriptionSelective, potent inhibitor of Akt activation
- API 2
- NSC 154020
Biological descriptionCell-permeable tricyclic nucleoside that inhibits the phosphorylation, activation and signalling of Akt. Selective over PKC, PKA, SGK and p38 pathways. Induces cell growth arrest and apoptosis in vitro.
Storage instructionsStore at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in DMSO to 75 mM and in ethanol to 10 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab120936 has not yet been referenced specifically in any publications.