Key features and details
- Rabbit polyclonal to TRIM71/LIN41
- Suitable for: ICC/IF, WB, ICC
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Product nameAnti-TRIM71/LIN41 antibody
See all TRIM71/LIN41 primary antibodies
DescriptionRabbit polyclonal to TRIM71/LIN41
Tested applicationsSuitable for: ICC/IF, WB, ICCmore details
Species reactivityReacts with: Mouse, Rat, Human
Synthetic peptide corresponding to Human TRIM71/LIN41 (C terminal).
Database link: NP_001034200
- Human brain tissue lysate
This product was previously labelled as TRIM71
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C.
Storage bufferpH: 7.2
Preservative: 0.02% Sodium azide
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab105330 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ICC/IF||Use a concentration of 20 µg/ml.|
|WB||Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 93 kDa.|
|ICC||Use a concentration of 5 µg/ml.|
FunctionE3 ubiquitin-protein ligase that cooperates with the microRNAs (miRNAs) machinery and promotes embryonic stem cells proliferation and maintenance. Binds to miRNAs and associates with AGO2, participating in post-transcriptional repression of transcripts such as CDKN1A. Facilitates the G1-S transition to promote rapid embryonic stem cell self-renewal by repressing CDKN1A expression. Required to maintain proliferation and prevent premature differentiation of neural progenitor cells during early neural development: positively regulates FGF signaling by controlling the stability of SHCBP1.
Tissue specificitySpecifically expressed in testis.
PathwayProtein modification; protein ubiquitination.
Sequence similaritiesBelongs to the TRIM/RBCC family.
Contains 2 B box-type zinc fingers.
Contains 1 filamin repeat.
Contains 6 NHL repeats.
Contains 1 RING-type zinc finger.
Cellular localizationCytoplasm, P-body.
- Information by UniProt
- 2610206G21Rik antibody
- Abnormal cell LINeage LIN 41 antibody
- AL022943 antibody
Lane 1 : Anti-TRIM71/LIN41 antibody (ab105330) at 1 µg/ml
Lane 2 : Anti-TRIM71/LIN41 antibody (ab105330) at 2 µg/ml
All lanes : Human brain tissue lysate
Lysates/proteins at 15 µg per lane.
All lanes : Anti-rabbit secondary antibody
Predicted band size: 93 kDa
Immunohistochemistry of TRIM71/LIN41 in human brain tissue with ab105330 at 5 µg/ml.
Immunofluorescence of TRIM71/LIN41 in Human Brain cells using ab105330 at 20 ug/ml.
ab105330 has been referenced in 1 publication.
- Robinton DA et al. The Lin28/let-7 Pathway Regulates the Mammalian Caudal Body Axis Elongation Program. Dev Cell 48:396-405.e3 (2019). PubMed: 30661985