Key features and details
- Rabbit polyclonal to TRIM71/LIN41
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-TRIM71/LIN41 antibody
See all TRIM71/LIN41 primary antibodies
DescriptionRabbit polyclonal to TRIM71/LIN41
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat
Synthetic peptide within Human TRIM71/LIN41 (internal sequence). The exact sequence is proprietary.
Database link: Q2Q1W2
- Human liver lysate.
This product was previously labelled as TRIM71
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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FormLyophilized:200 µl steriled distilled water.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 98% PBS, 1% BSA
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab176898 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/1000. Predicted molecular weight: 93 kDa.|
FunctionE3 ubiquitin-protein ligase that cooperates with the microRNAs (miRNAs) machinery and promotes embryonic stem cells proliferation and maintenance. Binds to miRNAs and associates with AGO2, participating in post-transcriptional repression of transcripts such as CDKN1A. Facilitates the G1-S transition to promote rapid embryonic stem cell self-renewal by repressing CDKN1A expression. Required to maintain proliferation and prevent premature differentiation of neural progenitor cells during early neural development: positively regulates FGF signaling by controlling the stability of SHCBP1.
Tissue specificitySpecifically expressed in testis.
PathwayProtein modification; protein ubiquitination.
Sequence similaritiesBelongs to the TRIM/RBCC family.
Contains 2 B box-type zinc fingers.
Contains 1 filamin repeat.
Contains 6 NHL repeats.
Contains 1 RING-type zinc finger.
Cellular localizationCytoplasm, P-body.
- Information by UniProt
- 2610206G21Rik antibody
- Abnormal cell LINeage LIN 41 antibody
- AL022943 antibody
ab176898 has not yet been referenced specifically in any publications.