Overview

  • Product name
  • Description
    Rabbit polyclonal to TRIM8
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Chicken, Cow, Xenopus laevis, Xenopus tropicalis
  • Immunogen

    Recombinant fragment corresponding to Human TRIM8 aa 17-242.
    Database link: Q9BZR9

  • Positive control
    • Human Hepatoma tissue; HepG2 whole cell lysate.
  • General notes

    Previously labelled as GERP. 

Properties

Applications

Our Abpromise guarantee covers the use of ab155674 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 61 kDa.
IHC-P 1/100 - 1/1000.

Target

  • Function
    Probable E3 ubiquitin-protein ligase which may promote proteasomal degradation of SOCS1.
  • Tissue specificity
    Widely expressed.
  • Pathway
    Protein modification; protein ubiquitination.
  • Sequence similarities
    Belongs to the TRIM/RBCC family.
    Contains 2 B box-type zinc fingers.
    Contains 1 RING-type zinc finger.
  • Domain
    The coiled coil domain is required for homodimerization.
    The region immediately C-terminal to the RING motif is sufficient to mediate the interaction with SOCS1.
  • Information by UniProt
  • Database links
  • Alternative names
    • AA408830 antibody
    • BB006755 antibody
    • GERP antibody
    • Glioblastoma-expressed RING finger protein antibody
    • Lioblastoma expressed ring finger protein antibody
    • Probable E3 ubiquitin-protein ligase TRIM8 antibody
    • RING finger protein 27 antibody
    • RNF27 antibody
    • RP11-47A8.4 antibody
    • TRIM8 antibody
    • TRIM8_HUMAN antibody
    • Tripartite motif containing 8 antibody
    • Tripartite motif protein TRIM8 antibody
    • Tripartite motif-containing protein 8 antibody
    see all

Images

  • Anti-TRIM8 antibody (ab155674) at 1/1000 dilution + HepG2 whole cell lysate at 30 µg

    Predicted band size: 61 kDa



    7.5% SDS PAGE
  • Immunohistochemical analysis of paraffin-embedded Human Hepatoma tissue, labeling TRIM8 with ab155674 at 1/500 dilution.

References

ab155674 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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