Overview

  • Product name

    Anti-TRM6 antibody
  • Description

    Rabbit polyclonal to TRM6
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to Human TRM6 aa 1-300.
    Database link: Q9UJA5

  • Positive control

    • WB: U-251 MG and HepG2 whole cell lysates. IHC-P: Human testis and adrenal gland tissues.
  • General notes

    Previously labelled as TRMT6. 

Properties

Applications

Our Abpromise guarantee covers the use of ab235321 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/5000. Predicted molecular weight: 56 kDa.
IHC-P 1/20 - 1/200.

Target

  • Function

    Substrate-binding subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.
  • Tissue specificity

    Expressed in brain, liver, testis and ovary.
  • Sequence similarities

    Belongs to the TRM6/GCD10 family.
  • Post-translational
    modifications

    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localization

    Nucleus.
  • Information by UniProt
  • Database links

  • Alternative names

    • KIAA1153 antibody
    • Adenine N antibody
    • CGI 09 antibody
    • CGI09 antibody
    • GCD10 antibody
    • Gcd10p antibody
    • MGC5029 antibody
    • TRM6 antibody
    • TRM6_HUMAN antibody
    • trmt6 antibody
    • tRNA (adenine-N(1)-)-methyltransferase non-catalytic subunit TRM6 antibody
    • tRNA methyltransferase 6 antibody
    • tRNA methyltransferase 6 homolog (S. cerevisiae) antibody
    • tRNA(m1A58)-methyltransferase subunit TRM6 antibody
    • tRNA(m1A58)MTase subunit TRM6 antibody
    see all

Images

  • All lanes : Anti-TRM6 antibody (ab235321) at 1/1000 dilution

    Lane 1 : U-251 MG (human brain glioma cell line) whole cell lysate
    Lane 2 : HepG2 (human liver hepatocellular carcinoma cell line) whole cell lysate

    Secondary
    All lanes : Goat polyclonal to Rabbit IgG at 1/10000 dilution

    Predicted band size: 56 kDa

  • Paraffin-embedded human testis tissue stained for TRM6 using ab235321 at 1/100 dilution in immunohistochemical analysis.

  • Paraffin-embedded human adrenal gland tissue stained for TRM6 using ab235321 at 1/100 dilution in immunohistochemical analysis.

References

ab235321 has not yet been referenced specifically in any publications.

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