Overview

  • Product name

    Trolox, Antioxidant vitamin E derivative
  • Description

    Antioxidant vitamin E derivative
  • Biological description

    Antioxidant vitamin E derivative. Exhibits lipid peroxidizing, DPPH° scavenging and HO° scavenging activity. Regularly used as an antioxidant standard. Cell-permeable and water soluble.
  • Purity

    > 98%
  • CAS Number

    53188-07-1
  • Chemical structure

    Chemical Structure

Properties

Images

  • Endothelial cells were cocultured with Nef-transfected Jurkat cells for 24 h, and then treated with apocynin (200 nM), trolox (200 nM), Nox2 inhibitor (1 µM) or IKKi (100 nM) and incubated an additional 18 h, then analyzed for Nef-induced MCP-1 production (C) and apoptosis of endothelial cells (D). Data were expressed as fold MCP-1 production and apoptosis, normalized to the mean of control measurements.

References

This product has been referenced in:

  • Cetinkaya Y  et al. Synthesis and antioxidant properties of (3,4-dihydroxyphenyl)(2,3,4-trihydroxyphenyl)methanone and its derivatives. Arch Pharm (Weinheim) 345:323-34 (2012). Read more (PubMed: 22147548) »
  • Hsieh TJ  et al. Protective effect of methyl gallate from Toona sinensis (Meliaceae) against hydrogen peroxide-induced oxidative stress and DNA damage in MDCK cells. Food Chem Toxicol 42:843-50 (2004). Read more (PubMed: 15046831) »
  • Cos P  et al. Comparative study of eight well-known polyphenolic antioxidants. J Pharm Pharmacol 55:1291-7 (2003). Read more (PubMed: 14604473) »
See all 2 Publications for this product

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