Key features and details
- Rabbit polyclonal to TROP2
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-TROP2 antibody
See all TROP2 primary antibodies
DescriptionRabbit polyclonal to TROP2
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Predicted to work with: Pig
Synthetic peptide within Human TROP2 aa 150-250 conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
(Peptide available as
- WB: Recombinant Human TROP2 protein (ab114374), A549, PC3 and HeLa whole cell lysates.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.40
Preservative: 0.02% Sodium azide
Batches of this product that have a concentration < 1mg/ml may have BSA added as a stabilising agent. If you would like information about the formulation of a specific lot, please contact our scientific support team who will be happy to help.
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab58930 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 1 µg/ml. Detects a band of approximately 36 kDa (predicted molecular weight: 36 kDa).|
FunctionMay function as a growth factor receptor.
Tissue specificityPlacenta, pancreatic carcinoma cell lines.
Involvement in diseaseDefects in TACSTD2 are the cause of gelatinous drop-like corneal dystrophy (GDLD) [MIM:204870]; also known as lattice corneal dystrophy type III. GDLD is an autosomal recessive disorder characterized by grayish corneal amyloid deposits that cause severe visual impairment.
Sequence similaritiesBelongs to the EPCAM family.
Contains 1 thyroglobulin type-1 domain.
modificationsThe N-terminus is blocked.
- Information by UniProt
- Cell surface glycoprotein Trop 2 antibody
- Cell surface glycoprotein Trop-2 antibody
- Cell surface glycoprotein Trop2 antibody
All lanes : Anti-TROP2 antibody (ab58930) at 1 µg/ml
Lane 1 : A549 (Human lung adenocarcinoma epithelial cell line) Whole Cell Lysate
Lane 2 : PC3 (Human prostate carcinoma cell line) Whole Cell Lysate Whole Cell Lysate
Lane 3 : HeLa (Human epithelial carcinoma cell line) Whole Cell Lysate
Lysates/proteins at 10 µg per lane.
All lanes : Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution
Developed using the ECL technique.
Performed under reducing conditions.
Predicted band size: 36 kDa
Observed band size: 36 kDa
Exposure time: 5 minutes
Human Tumor-associated calcium signal transducer 2 precursor contains a number of potential glycosylation sites (SwissProt) which may explain the higher migration pattern observed.
ab58930 has been referenced in 1 publication.
- Klein-Scory S et al. New insights in the composition of extracellular vesicles from pancreatic cancer cells: implications for biomarkers and functions. Proteome Sci 12:50 (2014). WB ; Human . PubMed: 25469109