Recombinant
RabMAb

Recombinant Anti-TROP2 antibody [SP295], prediluted (ab228199)

Overview

  • Product name

    Anti-TROP2 antibody [SP295], prediluted
    See all TROP2 primary antibodies
  • Description

    Rabbit monoclonal [SP295] to TROP2, prediluted
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide within Human TROP2 aa 100-200 (internal sequence). The exact sequence is proprietary.
    Database link: P09758

  • Positive control

    • IHC-P: Human tonsil, skin, prostate, pancreas, breast, bladder, skin squamous cell carcinoma, prostate adenocarcinoma, lung squamous cell carcinoma, breast ductal cell carcinoma and bladder transitional cell carcinoma tissues.

Properties

  • Form

    Prediluted
  • Storage instructions

    Shipped at 4°C. Store at +4°C. Do Not Freeze.
  • Storage buffer

    pH: 7.6
    Preservative: 0.1% Sodium azide
    Constituents: Tris buffered saline, 1% BSA
  • Concentration information loading...
  • Purity

    Protein A/G purified
  • Purification notes

    Purified from TCS by protein A/G.
  • Clonality

    Monoclonal
  • Clone number

    SP295
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab228199 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/1.

Ready to use.

Boil tissue section in EDTA buffer, pH 8.0 for 10 minutes followed by cooling at room temperature for 20 minutes.

Primary antibody incubation for 10 minutes at room temperature.

Target

  • Function

    May function as a growth factor receptor.
  • Tissue specificity

    Placenta, pancreatic carcinoma cell lines.
  • Involvement in disease

    Defects in TACSTD2 are the cause of gelatinous drop-like corneal dystrophy (GDLD) [MIM:204870]; also known as lattice corneal dystrophy type III. GDLD is an autosomal recessive disorder characterized by grayish corneal amyloid deposits that cause severe visual impairment.
  • Sequence similarities

    Belongs to the EPCAM family.
    Contains 1 thyroglobulin type-1 domain.
  • Post-translational
    modifications

    The N-terminus is blocked.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • Cell surface glycoprotein Trop 2 antibody
    • Cell surface glycoprotein Trop-2 antibody
    • Cell surface glycoprotein Trop2 antibody
    • Epithelial glycoprotein 1 antibody
    • GA733 1 antibody
    • GA7331 antibody
    • M1S 1 antibody
    • M1S1 antibody
    • Membrane component chromosome 1 surface marker 1 antibody
    • Pancreatic carcinoma marker protein GA733 1 antibody
    • Pancreatic carcinoma marker protein GA733-1 antibody
    • Pancreatic carcinoma marker protein GA7331 antibody
    • TACD 2 antibody
    • TACD2_HUMAN antibody
    • TACSTD 2 antibody
    • Tacstd2 antibody
    • Trop 2 antibody
    • Trop2 antibody
    • Tumor associated calcium signal transducer 2 precursor antibody
    • Tumor-associated calcium signal transducer 2 antibody
    see all

Images

  • Formalin-fixed, paraffin-embedded human tonsil tissue stained for TROP2 using ab228199 in immunohistochemical analysis.

  • Formalin-fixed, paraffin-embedded human skin tissue stained for TROP2 using ab228199 in immunohistochemical analysis.

  • Formalin-fixed, paraffin-embedded human skin squamous cell carcinoma tissue stained for TROP2 using ab228199 in immunohistochemical analysis.

  • Formalin-fixed, paraffin-embedded human prostate tissue stained for TROP2 using ab228199 in immunohistochemical analysis.

  • Formalin-fixed, paraffin-embedded human prostate adenocarcinoma tissue stained for TROP2 using ab228199 in immunohistochemical analysis.

  • Formalin-fixed, paraffin-embedded human pancreas tissue stained for TROP2 using ab228199 in immunohistochemical analysis.

  • Formalin-fixed, paraffin-embedded human lung squamous cell carcinoma tissue stained for TROP2 using ab228199 in immunohistochemical analysis.

  • Formalin-fixed, paraffin-embedded human breast tissue stained for TROP2 using ab228199 in immunohistochemical analysis.

  • Formalin-fixed, paraffin-embedded human breast ductal cell carcinoma tissue stained for TROP2 using ab228199 in immunohistochemical analysis.

  • Formalin-fixed, paraffin-embedded human bladder tissue stained for TROP2 using ab228199 in immunohistochemical analysis.

  • Formalin-fixed, paraffin-embedded human bladder transitional cell carcinoma tissue stained for TROP2 using ab228199 in immunohistochemical analysis.

References

ab228199 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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