Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR14926] to Troponin I fast skeletal muscle
- Suitable for: WB
- Reacts with: Mouse, Rat, Human
Product nameAnti-Troponin I fast skeletal muscle antibody [EPR14926]
See all Troponin I fast skeletal muscle primary antibodies
DescriptionRabbit monoclonal [EPR14926] to Troponin I fast skeletal muscle
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Mouse, Rat, Human
Synthetic peptide within Human Troponin I fast skeletal muscle aa 1-100. The exact sequence is proprietary.
Database link: P48788
- Human skeletal muscle lysate.
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.01% Sodium azide
Constituents: 59% PBS, 40% Glycerol, 0.05% BSA
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab183508 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/10000 - 1/100000. Detects a band of approximately 21 kDa (predicted molecular weight: 21 kDa).|
FunctionTroponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
Involvement in diseaseDefects in TNNI2 are a cause of distal arthrogryposis type 2B (DA2B) [MIM:601680]; also known as arthrogryposis multiplex congenita, distal, type 2B (AMCD2B). DA2B is a form of inherited multiple congenital contractures. Affected individuals have vertical talus, ulnar deviation in the hands, severe camptodactyly, and a distinctive face characterized by a triangular shape, prominent nasolabial folds, small mouth and a prominent chin.
Sequence similaritiesBelongs to the troponin I family.
- Information by UniProt
- AMCD 2B antibody
- AMCD2B antibody
- DA 2B antibody
Anti-Troponin I fast skeletal muscle antibody [EPR14926] (ab183508) at 1/100000 dilution + Human skeletal muscle lysate at 20 µg
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution
Predicted band size: 21 kDa
Additional bands at: 21 kDa. We are unsure as to the identity of these extra bands.
ab183508 has not yet been referenced specifically in any publications.