Trovafloxacin mesylate, Fluoroquinolone antibiotic agent (ab144562)

Overview

  • Product name
    Trovafloxacin mesylate, Fluoroquinolone antibiotic agent
  • Description
    Fluoroquinolone antibiotic agent. Topoisomerase IV and DNA gyrase inhibitor.
  • Biological description
    Fluoroquinolone antibiotic agent. Topoisomerase IV and DNA gyrase inhibitor. Reversibly inhibits DNA synthesis. Inhibits PANX1 (IC50 = 4 μM). Shows antibiotic effects in vivo (MIC90 = 244 nM, pneumococci).
  • Purity
    > 98%

Properties

References

This product has been referenced in:
  • Takac MJ Effects of substituents on the NMR features of basic bicyclic ring systems of fluoroquinolone antibiotics and the relationships between NMR chemical shifts, molecular descriptors and drug-likeness parameters. Acta Pharm 60:237-54 (2010). Read more (PubMed: 21134860) »
  • Goldstein EJ  et al. In vitro activity of gemifloxacin (SB 265805) against anaerobes. Antimicrob Agents Chemother 43:2231-5 (1999). Read more (PubMed: 10471570) »
  • Gootz TD  et al. Activity of the new fluoroquinolone trovafloxacin (CP-99,219) against DNA gyrase and topoisomerase IV mutants of Streptococcus pneumoniae selected in vitro. Antimicrob Agents Chemother 40:2691-7 (1996). Read more (PubMed: 9124824) »

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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