Product nameTRPA1 peptide
See all TRPA1/TSA proteins and peptides
Our Abpromise guarantee covers the use of ab204483 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
This is the blocking peptide for ab62053.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at -20°C.
- ANKTM 1
- Ankyrin-like with transmembrane domains protein 1
FunctionReceptor-activated non-selective cation channel involved in detection of pain and possibly also in cold perception and inner ear function. Has a central role in the pain response to endogenous inflammatory mediators and to a diverse array of volatile irritants, such as mustard oil, garlic and acrolein, an irritant from tears gas and vehicule exhaust fumes. Acts also as a ionotropic cannabinoid receptor by being activated by delta(9)-tetrahydrocannabinol (THC), the psychoactive component of marijuana. Not involved in menthol sensation. May be a component for the mechanosensitive transduction channel of hair cells in inner ear, thereby participating in the perception of sounds. Probably operated by a phosphatidylinositol second messenger system.
Tissue specificityExpressed at very low level. Expressed at very low level in human fibroblasts and at a moderate level in liposarcoma cells.
Sequence similaritiesBelongs to the transient receptor (TC 1.A.4) family.
Contains 15 ANK repeats.
- Information by UniProt
ab204483 has not yet been referenced specifically in any publications.