Key features and details
- Rabbit polyclonal to TRPC4AP
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-TRPC4AP antibody
DescriptionRabbit polyclonal to TRPC4AP
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat, Cow
Recombinant fragment, corresponding to a region within amino acids 81-294 of Human TRPC4AP (UniProt: Q8TEL6).
- A549, HeLa, HepG2 and HCT116 whole cell lysates.
Storage instructionsShipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab153810 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/3000. Predicted molecular weight: 91 kDa.|
FunctionSubstrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control. The DCX(TRUSS) complex specifically mediates the polyubiquitination and subsequent degradation of MYC. Also participates in the activation of NFKB1 in response to ligation of TNFRSF1A, possibly by linking TNFRSF1A to the IKK signalosome. Involved in JNK activation via its interaction with TRAF2. Also involved in elevation of endoplasmic reticulum Ca(2+) storage reduction in response to CHRM1.
PathwayProtein modification; protein ubiquitination.
- Information by UniProt
- C20orf188 antibody
- TRPC4AP antibody
- Chromosome 20 open reading frame 188 antibody
ab153810 has not yet been referenced specifically in any publications.