Question (73087) | Anti-TRPC6 antibody (ab62461)

Go to datasheet (ab62461)

Question

What is the amino acid sequence of the immunogen (ab106953) used to generate the TRPC6 antibody ab62461? What is the homology with rat TRPC6?

Answer

I was not able to obtain the exact sequence of the immunogen, as it is considered proprietary by our source for this antibody. I did learn that the immunogen shares 92% identity with rat TRPC6. There are 13 contiguous identical amino acids out of 14.

However, the lab also reported that a western blot of rat heart was negative. This is a little surprising, given the high homology, but it was one test, and the result may have been unique to the batch that was tested.

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