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What is the amino acid sequence of the immunogen (ab106953) used to generate the TRPC6 antibody ab62461? What is the homology with rat TRPC6?
Asked on Mar 25 2013
I was not able to obtain the exact sequence of the immunogen, as it is considered proprietary by our source for this antibody. I did learn that the immunogen shares 92% identity with rat TRPC6. There are 13 contiguous identical amino acids out of 14.
However, the lab also reported that a western blot of rat heart was negative. This is a little surprising, given the high homology, but it was one test, and the result may have been unique to the batch that was tested.
Answered on Mar 25 2013