Key features and details
- Guinea pig polyclonal to TRPM6
- Suitable for: IHC-Fr
- Reacts with: Rat
- Isotype: IgG
Product nameAnti-TRPM6 antibody
DescriptionGuinea pig polyclonal to TRPM6
Host speciesGuinea pig
Tested applicationsSuitable for: IHC-Frmore details
Species reactivityReacts with: Rat
Predicted to work with: Mouse
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
Storage bufferPreservative: 0.05% Sodium azide
Constituents: PBS, Whole serum
Concentration information loading...
Our Abpromise guarantee covers the use of ab47017 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-Fr||1/100 - 1/1000.|
RelevanceTRPM6 is an essential ion channel and serine/threonine-protein kinase, and is crucial for magnesium homeostasis. TRPM6 also has an important role in epithelial magnesium transport and in the active magnesium absorption in the gut and kidney. The various isoforms of the type M6-kinase lack the ion channel region.
Cellular localizationMulti-pass membrane protein.
- CHAK2 antibody
- Channel kinase 2 antibody
- HMGX antibody
ab47017 has been referenced in 4 publications.
- Wu HY et al. Overexpression of microRNA-202-3p protects against myocardial ischemia-reperfusion injury through activation of TGF-ß1/Smads signaling pathway by targeting TRPM6. Cell Cycle 18:621-637 (2019). PubMed: 30810438
- Ferioli S et al. TRPM6 and TRPM7 differentially contribute to the relief of heteromeric TRPM6/7 channels from inhibition by cytosolic Mg2+and Mg·ATP. Sci Rep 7:8806 (2017). PubMed: 28821869
- Boyden LM et al. Mutations in kelch-like 3 and cullin 3 cause hypertension and electrolyte abnormalities. Nature 482:98-102 (2012). PubMed: 22266938
- Sipos F et al. Peripheral blood based discrimination of ulcerative colitis and Crohn's disease from non-IBD colitis by genome-wide gene expression profiling. Dis Markers 30:1-17 (2011). PubMed: 21508504