Overview

  • Product name

  • Description

    Goat polyclonal to TRPV3
  • Host species

    Goat
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide corresponding to Human TRPV3 aa 762-773 (internal sequence) (Cysteine residue). (Near C-Terminus) (NP_659505.1).
    Sequence:

    C-NKIQDSSRNNSK


    Database link: Q8NET8

  • Positive control

    • WB: HEK-293 lysate overexpressing Human TRPV3 with DYKDDDDK tag.

Properties

Applications

Our Abpromise guarantee covers the use of ab240452 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 - 1 µg/ml. Detects a band of approximately 90 kDa (predicted molecular weight: 91 kDa).

Target

  • Function

    Putative receptor-activated non-selective calcium permeant cation channel. It is activated by innocuous (warm) temperatures and shows an increased response at noxious temperatures greater than 39 degrees Celsius. Activation exhibits an outward rectification. May associate with TRPV1 and may modulate its activity.
  • Tissue specificity

    Abundantly expressed in CNS. Widely expressed at low levels. Detected in dorsal root ganglion (at protein level).
  • Sequence similarities

    Belongs to the transient receptor (TC 1.A.4) family. TrpV subfamily. TRPV3 sub-subfamily.
    Contains 3 ANK repeats.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • 1110036I10Rik antibody
    • MGC124324 antibody
    • MGC124325 antibody
    • Transient receptor potential cation channel subfamily V member 3 antibody
    • TrpV3 antibody
    • Trpv3 heat sensitive channel antibody
    • TRPV3_HUMAN antibody
    • Vanilloid receptor 3 antibody
    • Vanilloid receptor like 3 antibody
    • Vanilloid receptor-like 3 antibody
    • vanilloid receptor-related osmotically activated channel protein antibody
    • VRL 3 antibody
    • VRL-3 antibody
    • VRL3 antibody
    see all

Images

  • Lane 1 : Anti-TRPV3 antibody (ab240452) at 0.5 µg/ml
    Lane 2 : Anti-TRPV3 antibody (ab240452) at 1 mg/ml
    Lane 3 : anti- DYKDDDDK Tag at 1/10000 dilution

    Lane 1 : HEK-293 (human epithelial cell line from embryonic kidney) lysate (in RIPA buffer) overexpressing Human TRPV3 with DYKDDDDK tag
    Lane 2 : Mock-transfected HEK-293 lysate
    Lane 3 : HEK-293 lysate (in RIPA buffer) overexpressing Human TRPV3 with DYKDDDDK tag

    Lysates/proteins at 10 µg per lane.

    Developed using the ECL technique.

    Predicted band size: 91 kDa



    Primary incubations were for 1 hour.

References

ab240452 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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