Recombinant
RabMAb

Recombinant Anti-Trypsinogen antibody [EPR11665(B)] (ab166898)

Overview

  • Product name

    Anti-Trypsinogen antibody [EPR11665(B)]
    See all Trypsinogen primary antibodies
  • Description

    Rabbit monoclonal [EPR11665(B)] to Trypsinogen
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
    Unsuitable for: ICC,IHC-P or IP
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to residues in Human Trypsinogen (UniProt: P07478).

  • Positive control

    • Human pancreas lysate
  • General notes

     

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab166898 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 26 kDa.
  • Application notes
    Is unsuitable for ICC,IHC-P or IP.
  • Target

    • Relevance

      Trypsinogen has been shown to have certain intrinsic activity. It is usually considered, however, as the inactive precursor of trypsin which may be activated by removal of a terminal hexapeptide to yield single chain b trypsin. Subsequent limited autolysis produces other active forms having two or more peptide chains bound by disulfide bonds. The predominant forms are a trypsin, having two peptide chains and b, a single chain. Different activity and thermal stability are shown by a and b trypsin.
    • Cellular localization

      Secreted protein; extracellular space.
    • Database links

    • Alternative names

      • Pancreatic anionic trypsinogen antibody
      • Protease, serine, 2 antibody
      • PRSS2 antibody
      • TRYP8 antibody

    Images

    • Anti-Trypsinogen antibody [EPR11665(B)] (ab166898) at 1/1000 dilution + Human pancreas lysate at 10 µg

      Secondary
      Goat anti-rabbit HRP antibody at 1/2000 dilution

      Predicted band size: 26 kDa

    References

    This product has been referenced in:

    • Wolters-Eisfeld G  et al. Loss of complex O-glycosylation impairs exocrine pancreatic function and induces MODY8-like diabetes in mice. Exp Mol Med 50:133 (2018). Read more (PubMed: 30305605) »
    See 1 Publication for this product

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab166898.
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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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