Key features and details
- Indoloquinazoline alkaloid with broad pharmacological activity
- CAS Number: 13220-57-0
- Soluble in DMSO to 100 mM
- Form / State: Solid
Product nameTryptanthrin, immunomodulator
DescriptionIndoloquinazoline alkaloid with broad pharmacological activity
Indoloquinazoline alkaloid with broad pharmacological activity. Immunomodulatory activity. Blocks BV2 microglia activation in response to LPS. Inhibits pro-inflammatory cytockine production via Nrf2, HO-1 and NFκB pathways. Inhibits indoleamine 2,3-dioxygenase 2 (IC50 = 5-17 μM). Promotes neuronal differentiation of human neuroblastoma cells. Also reported to have anti-cancer, anti-microbial and anti-oxidant activity.
Storage instructionsShipped at Room Temperature. Store at -20°C. Store under desiccating conditions.
Solubility overviewSoluble in DMSO to 100 mM
Toxic, refer to SDS for further information.
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To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab269884 has not yet been referenced specifically in any publications.