Overview

  • Product name

    Anti-Tryptophan Hydroxylase/TPH antibody
    See all Tryptophan Hydroxylase/TPH primary antibodies
  • Description

    Rabbit polyclonal to Tryptophan Hydroxylase/TPH
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, ICC/IFmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Chicken, Dog, Xenopus laevis
  • Immunogen

    Recombinant fragment within Human Tryptophan Hydroxylase/TPH (internal sequence). The exact sequence is proprietary.
    Database link: P17752

  • Positive control

    • WB: HepG2 whole cell lysate. ICC/IF: SK-N-SH cells.
  • General notes

     This product was previously labelled as Tryptophan Hydroxylase

     

Properties

Applications

Our Abpromise guarantee covers the use of ab228588 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 51 kDa.
ICC/IF 1/100 - 1/1000.

Target

  • Tissue specificity

    Isoform 2 seems to be less widely expressed than isoform 1.
  • Pathway

    Aromatic compound metabolism; serotonin biosynthesis; serotonin from L-tryptophan: step 1/2.
  • Sequence similarities

    Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.
    Contains 1 ACT domain.
  • Information by UniProt
  • Database links

  • Alternative names

    • Indoleacetic acid 5 hydroxylase antibody
    • L tryptophan hydroxylase antibody
    • MGC119994 antibody
    • TPH 1 antibody
    • TPH antibody
    • TPH1 antibody
    • TPH1_HUMAN antibody
    • TPRH antibody
    • TRPH antibody
    • Tryptophan 5 hydroxylase 1 antibody
    • Tryptophan 5 monooxygenase 1 antibody
    • Tryptophan 5 monooxygenase antibody
    • Tryptophan 5-hydroxylase 1 antibody
    • Tryptophan 5-monooxygenase 1 antibody
    • Tryptophan hydroxylase 1 antibody
    see all

Images

  • Anti-Tryptophan Hydroxylase/TPH antibody (ab228588) at 1/1000 dilution + HepG2 (human liver hepatocellular carcinoma cell line) whole cell lysate at 30 µg

    Developed using the ECL technique.

    Predicted band size: 51 kDa



    10% SDS-PAGE

  • SK-N-SH (human neuroblastoma cell line) cells stained for Tryptophan Hydroxylase/TPH (green) using ab228588 at 1/1000 dilution in ICC/IF. Cells were fixed in 4% paraformaldehyde at RT for 15 minutes.

    Blue: Hoechst 33342 staining.

References

ab228588 has not yet been referenced specifically in any publications.

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There are currently no Customer reviews or Questions for ab228588.
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