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Rabbit polyclonal to Tryptophanyl tRNA synthetase - C-terminal
Predicted to work with:
Synthetic peptide within Human Tryptophanyl tRNA synthetase aa 228-258 (C terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
Database link: P23381
Jurkat cell line lysates.
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Preservative: 0.09% Sodium azide
Constituent: 99% PBS
Concentration information loading...
Immunogen affinity purified
ab173801 is purified through a protein A column, followed by peptide affinity purification.
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/100 - 1/500. Predicted molecular weight: 53 kDa.
Isoform 1, isoform 2 and T1-TrpRS have aminoacylation activity while T2-TrpRS lacks it. Isoform 2, T1-TrpRS and T2-TrpRS possess angiostatic activity whereas isoform 1 lacks it. T2-TrpRS inhibits fluid shear stress-activated responses of endothelial cells. Regulates ERK, Akt, and eNOS activation pathways that are associated with angiogenesis, cytoskeletal reorganization and shear stress-responsive gene expression.
Belongs to the class-I aminoacyl-tRNA synthetase family.
Contains 1 WHEP-TRS domain.
Proteolytic cleavage generates 2 forms; T1-TrpRS and T2-TrpRS.
Information by UniProt
Gamma 2 antibody
Western blot - Anti-Tryptophanyl tRNA synthetase antibody - C-terminal (ab173801)
Anti-MED29 antibody - C-terminal (
) at 1/100 dilution + Jurkat cell line lysates at 35 µg
Predicted band size:
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"