Key features and details
- Rabbit polyclonal to TSH
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-TSH antibody
See all TSH primary antibodies
DescriptionRabbit polyclonal to TSH
Tested applicationsSuitable for: IHC-Pmore details
Species reactivityReacts with: Human
Full length native protein (purified) corresponding to Human TSH.
- Human anterior pituitary tissue
This product is FOR RESEARCH USE ONLY. For commercial use, please contact firstname.lastname@example.org.Cytoplasmic staining pattern
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferpH: 7.60
Preservative: 0.1% Sodium azide
Constituents: PBS, 1% BSA
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab64378 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
RelevanceThyroid stimulating hormone, also known as thyrotropin, is secreted from cells in the anterior pituitary called thyrotrophs, finds its receptors on epithelial cells in the thyroid gland, and stimulates that gland to synthesize and release thyroid hormones. TSH is a glycoprotein hormone composed of two subunits which are non covalently bound to one another. The alpha subunit of TSH is also present in two other pituitary glycoprotein hormones, follicle stimulating hormone and luteinizing hormone, and, in primates, in the placental hormone chorionic gonadotropin. Each of these hormones also has a unique beta subunit, which provides receptor specificity. In other words, TSH is composed of alpha subunit bound to the TSH beta subunit, and TSH associates only with its own receptor. Free alpha and beta subunits have essentially no biological activity.
- CG ALPHA antibody
- CGA antibody
- Chorionic gonadotropin alpha polypeptide antibody
ab64378 has been referenced in 1 publication.
- Mathioudakis N et al. Expression of the pituitary stem/progenitor marker GFRa2 in human pituitary adenomas and normal pituitary. Pituitary 18:31-41 (2015). PubMed: 24402129