Overview

  • Product name

    Anti-TSPY1/TSPY antibody - C-terminal
    See all TSPY1/TSPY primary antibodies
  • Description

    Rabbit polyclonal to TSPY1/TSPY - C-terminal
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide within Human TSPY1/TSPY (C terminal). The exact sequence is proprietary. 20 amino acids. NP_003299.2.
    Database link: Q01534

  • Positive control

    • Human testis tissue; A20 cell lysate.
  • General notes

     This product was previously labelled as TSPY1

     

Properties

Applications

Our Abpromise guarantee covers the use of ab189962 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 35 kDa.
IHC-P Use a concentration of 5 µg/ml.

Target

  • Function

    May be involved in sperm differentiation and proliferation.
  • Tissue specificity

    Specifically expressed in testicular tissues. Isoform 1 and isoform 2 are expressed in spermatogonia and spermatocytes. Found in early testicular carcinoma in situ, spermatogonial cells in testicular tissues of 46,X,Y female and in prostate cancer cell lines.
  • Involvement in disease

    Note=TSPY is located in the gonadoblastoma critical region and is preferentially expressed in tumor germ cells of gonadoblastoma specimens. Expression also correlates with testicular seminoma and tumorigenesis of the prostate gland.
  • Sequence similarities

    Belongs to the nucleosome assembly protein (NAP) family.
  • Developmental stage

    Detected in 22-week old testis.
  • Post-translational
    modifications

    Phosphorylated.
  • Cellular localization

    Cytoplasm. Nucleus. Predominantly cytoplasmic. Also found in nucleus.
  • Information by UniProt
  • Database links

  • Alternative names

    • Cancer/testis antigen 78 antibody
    • CT78 antibody
    • DYS14 antibody
    • pJA 923 antibody
    • pJA923 antibody
    • Testis specific protein Y linked 1 antibody
    • Testis specific Y encoded protein 1 antibody
    • Testis-specific Y-encoded protein 1 antibody
    • TSPY 1 antibody
    • TSPY antibody
    • Tspy1 antibody
    • TSPY1_HUMAN antibody
    see all

Images

  • Lane 1 : Anti-TSPY1/TSPY antibody - C-terminal (ab189962) at 0.5 µg/ml
    Lane 2 : Anti-TSPY1/TSPY antibody - C-terminal (ab189962) at 1 µg/ml

    All lanes : A20 cell lysate

    Predicted band size: 35 kDa

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human testis tissue labeling TSPY1/TSPY with ab189962 at  5µg/ml.

References

ab189962 has not yet been referenced specifically in any publications.

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