TTA-A2, T-type voltage gated Ca2+ channel blocker (ab145559)
Overview
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Product name
TTA-A2, T-type voltage gated Ca2+ channel blocker -
Description
Potent and selective T-type voltage gated Ca2+ channel blocker -
Biological description
Potent, selective T-type voltage gated Ca2+ channel blocker (IC50 values are 89 nM and 4.1 μM for CaV3.1 at -80 and -100 mV holding potentials respectively). Shows antipulmonary hypertensive, soporific and other central effects in vivo. Orally active.
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Purity
> 99% -
Chemical structure
Properties
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Chemical name
2-(4-Cyclopropylphenyl)-N-[(1R)-1-[5-(2,2,2-trifluoroethoxy)pyridin-2-yl]ethyl]acetamide
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Molecular weight
378.39 -
Molecular formula
C20H21F3N2O2 -
PubChem identifier
53317097 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM
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Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C[C@H](C1=NC=C(C=C1)OCC(F)(F)F)NC(=O)CC2=CC=C(C=C2)C3CC3 -
Source
Synthetic
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Research areas
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (0)
ab145559 has not yet been referenced specifically in any publications.
