Key features and details
- Rabbit polyclonal to TTC11/FIS1 - N-terminal
- Suitable for: WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Product nameAnti-TTC11/FIS1 antibody - N-terminal
See all TTC11/FIS1 primary antibodies
DescriptionRabbit polyclonal to TTC11/FIS1 - N-terminal
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Mouse, Rat, Human
Predicted to work with: Cow
Previously labelled as TTC11.
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol, 49% PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab189846 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/2000. Predicted molecular weight: 17 kDa.|
FunctionPromotes the fragmentation of the mitochondrial network and its perinuclear clustering. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission.
Sequence similaritiesBelongs to the FIS1 family.
Contains 1 TPR repeat.
DomainThe C-terminus is required for mitochondrial or peroxisomal localization, while the N-terminus is necessary for mitochondrial or peroxisomal fission, localization and regulation of the interaction with DNM1L.
modificationsUbiquitinated by MARCH5.
Cellular localizationMitochondrion outer membrane. Peroxisome membrane.
- Information by UniProt
- 2010003O14Rik antibody
- CGI 135 antibody
- CGI135 antibody
All lanes : Anti-TTC11/FIS1 antibody - N-terminal (ab189846) at 1/500 dilution
Lane 1 : 293T cell line extract
Lane 2 : HepG2 cell line extract
Lane 3 : A549 cell line extract
Lane 4 : HeLa cell line extract
Lane 5 : MCF7 cell line extract
Lane 6 : Mouse spleen cell line extract
Lane 7 : Mouse kidney cell line extract
Predicted band size: 17 kDa
ab189846 has not yet been referenced specifically in any publications.