Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.2
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab185465 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/200 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.|
FunctionPolyglutamylase which preferentially modifies beta-tubulin. Involved in the side-chain initiation step of the polyglutamylation reaction rather than in the elongation step. Required for neurite growth.
Tissue specificityHighly expressed in the nervous system including spinal cord, thalamus, hippocampus, hypothalamus and cerebellum.
Sequence similaritiesBelongs to the tubulin--tyrosine ligase family.
Contains 1 TTL domain.
Cellular localizationCell projection > cilium. Cytoplasm > cytoskeleton > cilium basal body. Cell projection > dendrite. Perikaryon. In cells with primary cilia, found in both cilia and basal bodies. In neuronal cells, found in dendrites and perikaryon.
- Information by UniProt
- RP5-836J3.2 antibody
- Testis development protein NYD-SP30 antibody
- Ttll7 antibody
ab185465 has not yet been referenced specifically in any publications.