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Rabbit polyclonal to TTPA - C-terminal
Synthetic peptide corresponding to a region within C terminal amino acids 215-278 of Human TTPA (UniProt ID: P49638).
IMR32 whole cell lysate; MCF7 cells; Human gastric carcinoma tissue.
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Preservative: 0.01% Thimerosal (merthiolate) Constituents: 0.75% Glycine, 1.21% Tris, 10% Glycerol
Concentration information loading...
Immunogen affinity purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/3000. Predicted molecular weight: 32 kDa.
1/100 - 1/1000.
1/100 - 1/1000.
Binds alpha-tocopherol and enhances its transfer between separate membranes.
Involvement in disease
Defects in TTPA are the cause of ataxia with isolated vitamin E deficiency (AVED) [MIM:277460]. AVED is an autosomal recessive disease characterized by spinocerebellar degeneration. It causes ataxia and peripheral neuropathy that resembles Friedreich ataxia. AVED patients have markedly reduced plasma levels of vitamin E.
Contains 1 CRAL-TRIO domain.
Information by UniProt
Alpha-tocopherol transfer protein antibody
Western blot - Anti-TTPA antibody - C-terminal (ab155323)
Anti-TTPA antibody - C-terminal (ab155323) at 1/1000 dilution + IMR32 whole cell lysate at 30 µg
Predicted band size: 32 kDa 12% SDS PAGE
Immunocytochemistry/ Immunofluorescence - Anti-TTPA antibody - C-terminal (ab155323)
Immunofluorescence analysis of methanol-fixed MCF7 cells labeling TTPA using ab155323 at 1/500 dilution. Lower image shows cells co-stained with Hoechst 33342.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TTPA antibody - C-terminal (ab155323)
Immunohistochemical analysis of paraffin-embedded Human gastric carcinoma tissue labeling TTPA with ab155323 at 1/500 dilution
has not yet been referenced specifically in any publications.
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