Anti-TTYH2 antibody - N-terminal (ab189421)

Overview

  • Product name

    Anti-TTYH2 antibody - N-terminal
  • Description

    Rabbit polyclonal to TTYH2 - N-terminal
  • Host species

    Rabbit
  • Specificity

    At least four isoforms of TTYH2 are known to exist; ab189421 will only detect the two longest isoforms. This antibody is predicted to not cross-react with other TTYH family members.
  • Tested applications

    Suitable for: WB, IHC-P, ICC/IFmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to Human TTYH2 (N terminal). 14 amino acid peptide.
    Database link: Q9BSA4

  • Positive control

    • Human heart and kidney tissue: Human kidney tissue lysate.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    Preservative: 0.02% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG

Applications

Our Abpromise guarantee covers the use of ab189421 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 59 kDa.
IHC-P Use a concentration of 5 µg/ml.
ICC/IF Use a concentration of 20 µg/ml.

Target

  • Function

    Probable large-conductance Ca(2+)-activated chloride channel. May play a role in Ca(2+) signal transduction. May be involved in cell proliferation and cell aggregation.
  • Tissue specificity

    Expressed at higher level in brain and testis and at lower levels in heart, ovary, spleen and peripheral blood leukocytes. Up-regulated in 13 of 16 renal cell carcinoma samples examined. Up-regulated in colon carcinoma.
  • Sequence similarities

    Belongs to the tweety family.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • C17orf29 antibody
    • hTTY2 antibody
    • Protein tweety homolog 2 antibody
    • Ttyh2 antibody
    • TTYH2_HUMAN antibody
    • Tweety family member 2 antibody
    • Tweety homolog 2 antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded human heart tissue labeling TTYH2 with ab189421 at 5 µg/ml.

  • Immunofluorescent analysis of human kidney tissue labeling TTYH2 with ab189421 at 20 µg/ml.

  • Anti-TTYH2 antibody - N-terminal (ab189421) at 1 µg/ml + Human kidney tissue lysate

    Predicted band size: 59 kDa

References

ab189421 has not yet been referenced specifically in any publications.

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