Overview

  • Product name

    Tubeimoside I, anticancer activity
  • Description

    Anti-inflammatory, apoptotic and antitumor agent
  • Biological description

    Shows anti-inflammatory, apoptotic and antitumor effects in vivo. Activates caspase, p53 Fas, TNFα, NF-κB and JNK pathways. Regulates Bcl-2, Bak and Bax. Induces ROS accumulation and arrests cell cycle at the G2/M phase.
  • Purity

    > 96%
  • CAS Number

    102040-03-9
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Yin Y  et al. NF-?B, JNK and p53 pathways are involved in tubeimoside-1-induced apoptosis in HepG2 cells with oxidative stress and G2/M cell cycle arrest. Food Chem Toxicol 49:3046-54 (2011). Read more (PubMed: 22005259) »
  • Yang P  et al. [Cell cycle arrest and apoptosis induced by tubeimoside in HeLa cell]. Ai Zheng 21:346-50 (2002). Read more (PubMed: 12452008) »
  • Yu TX  et al. Structure-activity relationship of tubeimosides in anti-inflammatory, antitumor, and antitumor-promoting effects. Acta Pharmacol Sin 22:463-8 (2001). Read more (PubMed: 11743898) »

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