The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/250. PubMed: 19706789
Tuberoinfundibular peptide of 39 residues (TIP39) was initially identified as a neurotransmitter and agonist of the PTH2 receptor, which is expressed in the cardiovascular system. Accumulating evidence suggests that TIP39 may be the endogenous ligand of the parathyroid hormone 2 receptor. The vast majority of TIP39 containing neurons are localized in two regions, the subparafascicular area at the thalamic midbrain junction, and the medial paralemniscal nucleus in the rostral pons. In contrast to the restricted localization of TIP39 containing cell bodies, TIP39 containing fibers have a widespread distribution.
Panda D et al. TIP39/parathyroid hormone type 2 receptor signaling is a potent inhibitor of chondrocyte proliferation and differentiation. Am J Physiol Endocrinol Metab297:E1125-36 (2009).
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