Product nameAnti-TUSC2/FUS1 antibody
See all TUSC2/FUS1 primary antibodies
DescriptionRabbit polyclonal to TUSC2/FUS1
Tested applicationsSuitable for: WB, ELISAmore details
Species reactivityReacts with: Mouse, Human
Synthetic peptide corresponding to Human TUSC2/FUS1 (internal sequence).
- extracts from HeLa cells.
This product was previously labelled as TUSC2
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferpH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol, 0.87% Sodium chloride, PBS
Without Mg2+ and Ca2+
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab70182 in the following tested applications.
|WB||1/500 - 1/1000. Detects a band of approximately >19 kDa (predicted molecular weight: 12 kDa).|
FunctionMay function as a tumor suppressor, inhibiting colony formation, causing G1 arrest and ultimately inducing apoptosis in homozygous 3p21.3 120-kb region-deficient cells.
Tissue specificityStrong expression in heart, lung, skeletal muscle, kidney, and pancreas, followed by brain and liver, lowest levels in placenta.
Sequence similaritiesBelongs to the TUSC2 family.
modificationsMyristoylation is required for tumor suppressor activity.
- Information by UniProt
- C3orf11 antibody
- Fus-1 protein antibody
- FUS1 antibody
All lanes : Anti-TUSC2/FUS1 antibody (ab70182) at 1/500 dilution
Lane 1 : HeLa cell extract
Lane 2 : HeLa cell extract with immunising peptide at 5 µg
Lysates/proteins at 5 µg per lane.
Predicted band size: 12 kDa
Observed band size: <19 kDa why is the actual band size different from the predicted?
This product has been referenced in:
- Liu F et al. TUSC2P suppresses the tumor function of esophageal squamous cell carcinoma by regulating TUSC2 expression and correlates with disease prognosis. BMC Cancer 18:894 (2018). Read more (PubMed: 30219035) »
- Yamamoto K et al. Uncovering Direct Targets of MiR-19a Involved in Lung Cancer Progression. PLoS One 10:e0137887 (2015). WB ; Human . Read more (PubMed: 26367773) »