Overview

  • Product name

    TWS119, GSK-3beta inhibitor
  • Description

    Potent cell-permeable GSK-3β inhibitor
  • Biological description

    Potent cell-permeable GSK-3β inhibitor (IC50 = 30 nM). Induces stem cell neurogenesis in vitro.
  • Purity

    > 95%
  • CAS Number

    601514-19-6
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Li YS  et al. ß-catenin accumulation in nuclei of hepatocellular carcinoma cells up-regulates glutathione-s-transferase M3 mRNA. World J Gastroenterol 17:1772-8 (2011). Read more (PubMed: 21483640) »
  • Kordes C  et al. Canonical Wnt signaling maintains the quiescent stage of hepatic stellate cells. Biochem Biophys Res Commun 367:116-23 (2008). Read more (PubMed: 18158920) »
  • Ding S  et al. Synthetic small molecules that control stem cell fate. Proc Natl Acad Sci U S A 100:7632-7 (2003). Read more (PubMed: 12794184) »

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