Key features and details
- Rabbit polyclonal to TXNDC/TMX
- Suitable for: ICC/IF, WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-TXNDC/TMX antibody
See all TXNDC/TMX primary antibodies
DescriptionRabbit polyclonal to TXNDC/TMX
Tested applicationsSuitable for: ICC/IF, WB, IHC-Pmore details
Species reactivityReacts with: Human
- WB: CAPAN-2 cell lysate. IHC-P: Human small intestine, testis and endometrium tissue. ICC/IF: U-2 OS cells.
This product was previously labelled as TXNDC
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.20
Preservative: 0.02% Sodium azide
Constituents: PBS, 40% Glycerol (glycerin, glycerine)
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab244263 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ICC/IF||Use a concentration of 0.25 - 2 µg/ml.
Fixation/Permeabilization: PFA/Triton X-100.
|WB||Use a concentration of 0.04 - 0.4 µg/ml. Predicted molecular weight: 32 kDa.|
|IHC-P||1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.|
FunctionMay participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions.
Tissue specificityUbiquitous. Highly expressed in kidney, liver, placenta and lung.
Sequence similaritiesContains 1 thioredoxin domain.
Cellular localizationMembrane. Endoplasmic reticulum membrane. Predominantly found in the endoplasmic reticulum.
- Information by UniProt
- PDIA11 antibody
- Protein disulfide isomerase family A, member 11 antibody
- Thioredoxin domain containing 1 antibody
PFA-fixed, Triton X-100 permeabilized U-2 OS (human bone osteosarcoma epithelial cell line) cells stained for TXNDC/TMX (green) using ab244263 at 4 µg/ml in ICC/IF.
Formalin-fixed, paraffin-embedded human testis tissue stained for TXNDC/TMX using ab244263 at 1/200 dilution in immunohistochemical analysis.
Anti-TXNDC/TMX antibody (ab244263) at 0.4 µg/ml + CAPAN-2 cell lysate
Predicted band size: 32 kDa
Formalin-fixed, paraffin-embedded human small intestine tissue stained for TXNDC/TMX using ab244263 at 1/200 dilution in immunohistochemical analysis.
Formalin-fixed, paraffin-embedded human endometrium tissue stained for TXNDC/TMX using ab244263 at 1/200 dilution in immunohistochemical analysis.
Formalin-fixed, paraffin-embedded human skeletal muscle tissue stained for TXNDC/TMX using ab244263 at 1/200 dilution in immunohistochemical analysis.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab244263 has not yet been referenced specifically in any publications.