Overview

  • Product name
  • Description
    Rabbit polyclonal to TXNRD2
  • Host species
    Rabbit
  • Tested applications
    Suitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Rat
  • Positive control
    • Rat kidney microsomal preparation. Liver carcinoma.

Properties

Applications

Our Abpromise guarantee covers the use of ab15173 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
WB Use at an assay dependent concentration. Predicted molecular weight: 56 kDa.

Target

  • Function
    Maintains thioredoxin in a reduced state. Implicated in the defenses against oxidative stress. May play a role in redox-regulated cell signaling.
  • Tissue specificity
    Highly expressed in the prostate, ovary, liver, testis, uterus, colon and small intestine. Intermediate levels in brain, skeletal muscle, heart and spleen. Low levels in placenta, pancreas, thymus and peripheral blood leukocytes. According to PubMed:10608886, high levels in kidney, whereas according to PubMed:9923614, levels are low.
  • Sequence similarities
    Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
  • Cellular localization
    Mitochondrion.
  • Information by UniProt
  • Database links
  • Alternative names
    • mitochondrial antibody
    • Selenoprotein Z antibody
    • SelZ antibody
    • Thioredoxin reductase 2 antibody
    • Thioredoxin reductase 2 mitochondrial antibody
    • Thioredoxin reductase 3 antibody
    • Thioredoxin reductase beta antibody
    • Thioredoxin reductase TR3 antibody
    • TR 3 antibody
    • TR antibody
    • TR beta antibody
    • TR-beta antibody
    • TR3 antibody
    • TRXR 2 antibody
    • TRXR2 antibody
    • TRXR2_HUMAN antibody
    • TXNRD 2 antibody
    • Txnrd2 antibody
    see all

References

ab15173 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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