Key features and details
- Rabbit polyclonal to TXNRD2
- Suitable for: WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Product nameAnti-TXNRD2 antibody
See all TXNRD2 primary antibodies
DescriptionRabbit polyclonal to TXNRD2
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Mouse, Rat, Human
Recombinant full length protein (Human).
- Jurkat whole cell lysate, rat lung lysate, mouse liver lysate.
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferConstituents: PBS, 50% Glycerol
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab16841 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/2000. Predicted molecular weight: 56 kDa.|
FunctionMaintains thioredoxin in a reduced state. Implicated in the defenses against oxidative stress. May play a role in redox-regulated cell signaling.
Tissue specificityHighly expressed in the prostate, ovary, liver, testis, uterus, colon and small intestine. Intermediate levels in brain, skeletal muscle, heart and spleen. Low levels in placenta, pancreas, thymus and peripheral blood leukocytes. According to PubMed:10608886, high levels in kidney, whereas according to PubMed:9923614, levels are low.
Sequence similaritiesBelongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
- Information by UniProt
- mitochondrial antibody
- Selenoprotein Z antibody
- SelZ antibody
All lanes : Anti-TXNRD2 antibody (ab16841) at 1/2000 dilution
Lane 1 : Jurkat lysate
Lane 2 : Mouse liver lysate
Lane 3 : Rat lung lysate
Predicted band size: 56 kDa
ab16841 at 1/2000 dilution staining TXNRD2 by Western blot.
Lane 1: Jurkat cell lysates.
Lane 2: Mouse liver.
Lane 3: Rat lung.
ab16841 has been referenced in 2 publications.
- Hauck L et al. Cardiac-specific ablation of the E3 ubiquitin ligase Mdm2 leads to oxidative stress, broad mitochondrial deficiency and early death. PLoS One 12:e0189861 (2017). PubMed: 29267372
- Zhao X et al. Variations of thioredoxin system contributes to increased susceptibility to apoptosis in cardiomyocytes of type 2 diabetic rats. Acta Biochim Biophys Sin (Shanghai) 46:318-29 (2014). PubMed: 24578161